(Source: American College of Cardiology Foundation) The following are key points to remember from this review of testosterone (T) and cardiovascular disease (CVD), hypogonadism, and testosterone replacement therapy (TRT): Testosterone (T) is the principal male sex hormone whose androgenic effects are responsible for development of male sex organs and maturing characteristics including sex drive, muscle mass, strength, and bone density. Hypothalamic gonadotropin-releasing hormone (GnRH) stimulates luteinizing hormone (LH), which stimulates T synthesis and follicle stimulating hormone (FSH) that stimulates spermatogenesis. The majority of circulating T is bound to sex hormone-binding globulin...
↧